The implementation of screening for prostate cancer

Pim Leeuwen, Heidi Vugt, CH Bangma VERVALLEN

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)


The objective of this study was to determine whether screening for prostate cancer (PC) reduces PC mortality and, if so, whether the required criteria to be introduced as a population-based screening program are satisfied. A literature review was conducted through electronic scientific databases. The screening tests, that is, PSA and digital rectal examination, have limited sensitivity and specificity for detecting PC; screening produces a beneficial stage shift and reduces PC mortality. Nevertheless, PC screening causes a large increase in the cumulative incidence, and the understanding of the economic cost and quality-of-life parameters are limited. PC screening cannot be justified yet in the context of a public health policy. Prostate Cancer and Prostatic Diseases (2010) 13, 218-227; doi:10.1038/pcan.2010.14; published online 3 August 2010
Original languageUndefined/Unknown
Pages (from-to)218-227
Number of pages10
JournalProstate Cancer and Prostatic Diseases
Issue number3
Publication statusPublished - 2010

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