The implementation of screening for prostate cancer

Pim Leeuwen, Heidi Vugt, CH Bangma VERVALLEN

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)


The objective of this study was to determine whether screening for prostate cancer (PC) reduces PC mortality and, if so, whether the required criteria to be introduced as a population-based screening program are satisfied. A literature review was conducted through electronic scientific databases. The screening tests, that is, PSA and digital rectal examination, have limited sensitivity and specificity for detecting PC; screening produces a beneficial stage shift and reduces PC mortality. Nevertheless, PC screening causes a large increase in the cumulative incidence, and the understanding of the economic cost and quality-of-life parameters are limited. PC screening cannot be justified yet in the context of a public health policy. Prostate Cancer and Prostatic Diseases (2010) 13, 218-227; doi:10.1038/pcan.2010.14; published online 3 August 2010
Original languageUndefined/Unknown
Pages (from-to)218-227
Number of pages10
JournalProstate Cancer and Prostatic Diseases
Issue number3
Publication statusPublished - 2010

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