The influence of obesity on short- and long-term graft and patient survival after renal transplantation

Jeroen Aalten*, Maarten H. Christiaans, Hans De Fijter, Ronald Hené, Jaap Homan Van Der Heijde, Joke Roodnat, Janto Surachno, Andries Hoitsma

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

103 Citations (Scopus)


To determine short- and long-term patient and graft survival in obese [body mass index (BMI) ≥ 30 kg/m2] and nonobese (BMI < 30 kg/m 2) renal transplant patients we retrospectively analyzed our national-database. Patients 18 years or older receiving a primary transplant after 1993 were included. A total of 1871 patients were included in the nonobese group and 196 in the obese group. In the obese group there were significantly more females (52% vs. 38.6%, P < 0.01) and patients were significantly older [52 years (43-59) vs. 48 years (37-58); P < 0.05]. Patient survival and graft survival were significantly decreased in obese renal transplant recipients (1 and 5 year patient survival were respectively 94% vs. 97% and 81% vs. 89%, P < 0.01; 1 and 5 year graft survival were respectively 86% vs. 92% and 71% vs. 80%, P < 0.01). Initial BMI was an independent predictor for patient death and graft failure. This large retrospective study shows that both graft and patient survival are significantly lower in obese renal transplant recipients.

Original languageEnglish
Pages (from-to)901-907
Number of pages7
JournalTransplant International
Issue number11
Publication statusPublished - Nov 2006


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