TY - JOUR
T1 - The panzootic spread of highly pathogenic avian influenza H5N1 sublineage 2.3.4.4b
T2 - a critical appraisal of One Health preparedness and prevention
AU - Koopmans, Marion P.G.
AU - Barton Behravesh, Casey
AU - One Health High-Level Expert Panel (OHHLEP)
AU - Cunningham, Andrew A.
AU - Adisasmito, Wiku B.
AU - Almuhairi, Salama
AU - Bilivogui, Pépé
AU - Bukachi, Salome A.
AU - Casas, Natalia
AU - Cediel Becerra, Natalia
AU - Charron, Dominique F.
AU - Chaudhary, Abhishek
AU - Ciacci Zanella, Janice R.
AU - Dar, Osman
AU - Debnath, Nitish
AU - Dungu, Baptiste
AU - Farag, Elmoubasher
AU - Gao, George F.
AU - Khaitsa, Margaret
AU - Machalaba, Catherine
AU - Mackenzie, John S.
AU - Markotter, Wanda
AU - Mettenleiter, Thomas C.
AU - Morand, Serge
AU - Smolenskiy, Vyacheslav
AU - Zhou, Lei
AU - Hayman, David T.S.
N1 - Publisher Copyright:
© 2024 Elsevier Ltd
PY - 2024/12
Y1 - 2024/12
N2 - Changes in the epidemiology and ecology of H5N1 highly pathogenic avian influenza are devastating wild bird and poultry populations, farms and communities, and wild mammals worldwide. Having originated in farmed poultry, H5N1 viruses are now spread globally by wild birds, with transmission to many mammal and avian species, resulting in 2024 in transmission among dairy cattle with associated human cases. These ecological changes pose challenges to mitigating the impacts of H5N1 highly pathogenic avian influenza on wildlife, ecosystems, domestic animals, food security, and humans. H5N1 highly pathogenic avian influenza highlights the need for One Health approaches to pandemic prevention and preparedness, emphasising multisectoral collaborations among animal, environmental, and public health sectors. Action is needed to reduce future pandemic risks by preventing transmission of highly pathogenic avian influenza among domestic and wild animals and people, focusing on upstream drivers of outbreaks, and ensuring rapid responses and risk assessments for zoonotic outbreaks. Political commitment and sustainable funding are crucial to implementing and maintaining prevention programmes, surveillance, and outbreak responses.
AB - Changes in the epidemiology and ecology of H5N1 highly pathogenic avian influenza are devastating wild bird and poultry populations, farms and communities, and wild mammals worldwide. Having originated in farmed poultry, H5N1 viruses are now spread globally by wild birds, with transmission to many mammal and avian species, resulting in 2024 in transmission among dairy cattle with associated human cases. These ecological changes pose challenges to mitigating the impacts of H5N1 highly pathogenic avian influenza on wildlife, ecosystems, domestic animals, food security, and humans. H5N1 highly pathogenic avian influenza highlights the need for One Health approaches to pandemic prevention and preparedness, emphasising multisectoral collaborations among animal, environmental, and public health sectors. Action is needed to reduce future pandemic risks by preventing transmission of highly pathogenic avian influenza among domestic and wild animals and people, focusing on upstream drivers of outbreaks, and ensuring rapid responses and risk assessments for zoonotic outbreaks. Political commitment and sustainable funding are crucial to implementing and maintaining prevention programmes, surveillance, and outbreak responses.
UR - http://www.scopus.com/inward/record.url?scp=85201872706&partnerID=8YFLogxK
U2 - 10.1016/S1473-3099(24)00438-9
DO - 10.1016/S1473-3099(24)00438-9
M3 - Review article
AN - SCOPUS:85201872706
SN - 1473-3099
VL - 24
SP - e774-e781
JO - The Lancet Infectious Diseases
JF - The Lancet Infectious Diseases
IS - 12
ER -
