The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors

HT Pham; L Labrie; Ingeborg Wijting; S Hassounah; KY Lok; I Portna; ME Goring; YS Han; Cynthia Lungu; Marchina Ende; BG Brenner; Charles Boucher; Bart Rijnders; Jeroen van Kampen; T Mesplede; MA Wainberg

doi:10.1093/infdis/jiy175

The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors

HT Pham
, L Labrie
, Ingeborg Wijting
, S Hassounah
, KY Lok
, I Portna
, ME Goring
, YS Han
, Cynthia Lungu
, Marchina Ende
, BG Brenner
, Charles Boucher
, Bart Rijnders
, Jeroen van Kampen
, T Mesplede
, MA Wainberg

Research output: Contribution to journal › Article › Academic › peer-review

27 Citations (Scopus)

34 Downloads (Pure)

Original language	Undefined/Unknown
Pages (from-to)	698-706
Number of pages	9
Journal	Journal of Infectious Diseases
Volume	218
Issue number	5
DOIs	https://doi.org/10.1093/infdis/jiy175
Publication status	Published - 2018

Research programs

EMC MM-04-28-04

Access to Document

10.1093/infdis/jiy175

RePub-109907-OA.pdfFinal published version, 412 KB

http://hdl.handle.net/1765/109907

Cite this

Pham, HT., Labrie, L., Wijting, I., Hassounah, S., Lok, KY., Portna, I., Goring, ME., Han, YS., Lungu, C., Ende, M., Brenner, BG., Boucher, C., Rijnders, B., van Kampen, J., Mesplede, T., & Wainberg, MA. (2018). The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors. Journal of Infectious Diseases, 218(5), 698-706. https://doi.org/10.1093/infdis/jiy175

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author = "HT Pham and L Labrie and Ingeborg Wijting and S Hassounah and KY Lok and I Portna and ME Goring and YS Han and Cynthia Lungu and Marchina Ende and BG Brenner and Charles Boucher and Bart Rijnders and \{van Kampen\}, Jeroen and T Mesplede and MA Wainberg",

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doi = "10.1093/infdis/jiy175",

language = "Undefined/Unknown",

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Pham, HT, Labrie, L, Wijting, I, Hassounah, S, Lok, KY, Portna, I, Goring, ME, Han, YS, Lungu, C, Ende, M, Brenner, BG, Boucher, C, Rijnders, B , van Kampen, J, Mesplede, T & Wainberg, MA 2018, 'The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors', Journal of Infectious Diseases, vol. 218, no. 5, pp. 698-706. https://doi.org/10.1093/infdis/jiy175

TY - JOUR

T1 - The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors

AU - Pham, HT

AU - Labrie, L

AU - Wijting, Ingeborg

AU - Hassounah, S

AU - Lok, KY

AU - Portna, I

AU - Goring, ME

AU - Han, YS

AU - Lungu, Cynthia

AU - Ende, Marchina

AU - Brenner, BG

AU - Boucher, Charles

AU - Rijnders, Bart

AU - van Kampen, Jeroen

AU - Mesplede, T

AU - Wainberg, MA

PY - 2018

Y1 - 2018

U2 - 10.1093/infdis/jiy175

DO - 10.1093/infdis/jiy175

M3 - Article

C2 - 29617824

SN - 0022-1899

VL - 218

SP - 698

EP - 706

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

IS - 5

ER -