The spliceosome as target for anticancer treatment

RJ (Robbert) van Alphen; Erik Wiemer; Herman Burger; Ferry Eskens

doi:10.1038/sj.bjc.6604801

The spliceosome as target for anticancer treatment

RJ (Robbert) van Alphen, Erik Wiemer, Herman Burger, Ferry Eskens

Medical Oncology

Research output: Contribution to journal › Article › Academic › peer-review

81 Citations (Scopus)

Abstract

The spliceosome is a ribonucleoprotein complex involved in RNA splicing, that is, the removal of non-coding introns from precursor messenger RNA. (Alternative) Splicing events may play an essential role in tumourigenesis. The recent discovery that the spliceosome is a target for novel compounds with anticancer activity opens up new therapeutic avenues.

Original language	Undefined/Unknown
Pages (from-to)	228-232
Number of pages	5
Journal	British Journal of Cancer
Volume	100
Issue number	2
DOIs	https://doi.org/10.1038/sj.bjc.6604801
Publication status	Published - 2009

Access to Document

10.1038/sj.bjc.6604801

http://hdl.handle.net/1765/14194

Cite this

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title = "The spliceosome as target for anticancer treatment",

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