The use of botulinum toxin type A in cosmetic facial procedures

G W C Jaspers, J Pijpe, J Jansma

Research output: Contribution to journalReview articleAcademicpeer-review

44 Citations (Scopus)


Over the past decade, facial cosmetic procedures have become more commonplace in dentistry and oral and maxillofacial surgery. An increasing number of patients seek minimal invasive procedures. One of the most requested procedures is treatment with botulinum toxin type A (BoNTA). Treatment of dynamic rhytids and lines with BoNTA is effective and produces high rates of improvement with rapid onset and long duration of action (longer than 4 months for some patients) compared with placebo. This paper considers the history and pharmacology of this neurotoxin, and focusses on the literature concerning the treatment of different facial areas with BoNTA. It also presents clinical guidelines on the treatment of glabellar lines, the frontalis muscle, peri-orbital lines, gummy smile and masseter muscle hypertrophy. Knowledge about the mechanisms of action and the ability to use BoNTA as an adjunctive treatment are mandatory for those working in the field of cosmetic facial surgery.

Original languageEnglish
Pages (from-to)127-33
Number of pages7
JournalInternational Journal of Oral and Maxillofacial Surgery
Issue number2
Early online date22 Oct 2010
Publication statusPublished - Feb 2011
Externally publishedYes

Bibliographical note

Copyright © 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.


Dive into the research topics of 'The use of botulinum toxin type A in cosmetic facial procedures'. Together they form a unique fingerprint.

Cite this