The use of genomic tools for the molecular understanding of breast cancer and to guide personalized medicine

John Foekens, YX Wang, John Martens, Els Berns, Jan Klijn

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Abstract

The use of gene-expression microarray analysis to assess the expression levels of all the genes in the genome has tremendous potential. Important information has been obtained about many disease processes, particularly in classifying tumors in different subtypes and risk groups. Combining gene-expression data with other genomic information and the use of sophisticated bioinformatic tools enables the discovery of potential new targets for treatment, and is helpful for high-throughput drug screening and for designing new classes of drugs for targeted therapy. Here, we provide a short overview of the recent, promising developments in the field with emphasis on breast cancer.
Original languageUndefined/Unknown
Pages (from-to)481-487
Number of pages7
JournalDrug Discovery Today
Volume13
Issue number11-12
Publication statusPublished - 2008

Research programs

  • EMC MM-03-86-01

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