Third-line Life-prolonging Drug Treatment in a Real-world Metastatic Castration-resistant Prostate Cancer Population: Results from the Dutch Castration-resistant Prostate Cancer Registry

Jessica C.L. Notohardjo*, Malou C.P. Kuppen, Hans M. Westgeest, Reindert J.A. van Moorselaar, Niven Mehra, Jules L.L.M. Coenen, Inge M. van Oort, Aad I. de Vos, Walter L. Vervenne, Alphons C.M. van den Bergh, Katja K.H. Aben, Diederik M. Somford, Andries M. Bergman, Carin A. Uyl-de Groot, Winald R. Gerritsen, Alfons J.M. van den Eertwegh

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Abstract

Third-line life-prolonging drugs (LPDs) might not be appropriate for all metastatic castration-resistant prostate cancer patients. We developed a prognostic model and identified a high-risk subgroup in which no meaningful benefit from third-line LPDs is derived in clinical practice.

Original languageEnglish
JournalEuropean Urology Focus
DOIs
Publication statusAccepted/In press - 30 Apr 2020

Bibliographical note

Funding Information:
This research was funded by Sanofi-AventisNetherlands B.V., Janssen-Cilag B.V., Astellas Pharma B.V., and Bayer B.V. The funding organisations had no role in the design and conduct of thestudy; collection, management, analysis, and interpretation of the data;and preparation, review, or approval of the manuscript.

Publisher Copyright:
© 2020 European Association of Urology

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