Tissue-specific mutation accumulation in human adult stem cells during life

F Blokzijl; J de Ligt; M Jager; V Sasselli; S Roerink; N Sasaki; M Huch; S Boymans; E Kuijk; P Prins; IJ Nijman; I Martincorena; M Mokry; CL Wiegerinck; Sabine Middendorp; T Sato; G Schwank; EES Nieuwenhuis; Monique Verstegen; Luc van der Laan; Jeroen de Jonge; J.N.M. IJzermans; RG de Vries; M van de Wetering; MR Stratton; H Clevers; E Cuppen; R van Boxtel

doi:10.1038/nature19768

Tissue-specific mutation accumulation in human adult stem cells during life

F Blokzijl, J de Ligt, M Jager, V Sasselli, S Roerink, N Sasaki, M Huch, S Boymans, E Kuijk, P Prins, IJ Nijman, I Martincorena, M Mokry, CL Wiegerinck, Sabine Middendorp, T Sato, G Schwank, EES Nieuwenhuis, Monique Verstegen, Luc van der LaanJeroen de Jonge, J.N.M. IJzermans, RG de Vries, M van de Wetering, MR Stratton, H Clevers, E Cuppen, R van Boxtel

Surgery

Research output: Contribution to journal › Article › Academic › peer-review

559 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	260-+
Journal	Nature
Volume	538
Issue number	7624
DOIs	https://doi.org/10.1038/nature19768
Publication status	Published - 2016

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10.1038/nature19768

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Blokzijl, F., de Ligt, J., Jager, M., Sasselli, V., Roerink, S., Sasaki, N., Huch, M., Boymans, S., Kuijk, E., Prins, P., Nijman, IJ., Martincorena, I., Mokry, M., Wiegerinck, CL., Middendorp, S., Sato, T., Schwank, G., Nieuwenhuis, EES., Verstegen, M., ... van Boxtel, R. (2016). Tissue-specific mutation accumulation in human adult stem cells during life. Nature, 538(7624), 260-+. https://doi.org/10.1038/nature19768

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author = "F Blokzijl and {de Ligt}, J and M Jager and V Sasselli and S Roerink and N Sasaki and M Huch and S Boymans and E Kuijk and P Prins and IJ Nijman and I Martincorena and M Mokry and CL Wiegerinck and Sabine Middendorp and T Sato and G Schwank and EES Nieuwenhuis and Monique Verstegen and {van der Laan}, Luc and {de Jonge}, Jeroen and J.N.M. IJzermans and {de Vries}, RG and {van de Wetering}, M and MR Stratton and H Clevers and E Cuppen and {van Boxtel}, R",

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doi = "10.1038/nature19768",

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Blokzijl, F, de Ligt, J, Jager, M, Sasselli, V, Roerink, S, Sasaki, N, Huch, M, Boymans, S, Kuijk, E, Prins, P, Nijman, IJ, Martincorena, I, Mokry, M, Wiegerinck, CL, Middendorp, S, Sato, T, Schwank, G, Nieuwenhuis, EES, Verstegen, M , van der Laan, L , de Jonge, J , IJzermans, JNM, de Vries, RG, van de Wetering, M, Stratton, MR, Clevers, H, Cuppen, E & van Boxtel, R 2016, 'Tissue-specific mutation accumulation in human adult stem cells during life', Nature, vol. 538, no. 7624, pp. 260-+. https://doi.org/10.1038/nature19768

TY - JOUR

T1 - Tissue-specific mutation accumulation in human adult stem cells during life

AU - Blokzijl, F

AU - de Ligt, J

AU - Jager, M

AU - Sasselli, V

AU - Roerink, S

AU - Sasaki, N

AU - Huch, M

AU - Boymans, S

AU - Kuijk, E

AU - Prins, P

AU - Nijman, IJ

AU - Martincorena, I

AU - Mokry, M

AU - Wiegerinck, CL

AU - Middendorp, Sabine

AU - Sato, T

AU - Schwank, G

AU - Nieuwenhuis, EES

AU - Verstegen, Monique

AU - van der Laan, Luc

AU - de Jonge, Jeroen

AU - IJzermans, J.N.M.

AU - de Vries, RG

AU - van de Wetering, M

AU - Stratton, MR

AU - Clevers, H

AU - Cuppen, E

AU - van Boxtel, R

PY - 2016

Y1 - 2016

U2 - 10.1038/nature19768

DO - 10.1038/nature19768

M3 - Article

SN - 0028-0836

VL - 538

SP - 260-+

JO - Nature

JF - Nature

IS - 7624

ER -