Towards clinical application of urinary extracellular vesicles

Charles Blijdorp

Research output: Types of ThesisDoctoral ThesisInternal

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Abstract

Urinary vesicles (uEVs) are small particles that are found in urine and largely originate directly from the kidney. This thesis describes steps taken to make uEVs clinically applicable, by
(1) analyzing ways that allow for rapid and reliable analysis,
(2) investigating the effect of gender, kidney size and urine concentration on uEV excretion, and
(3) by the discovery of a uEV protein that can predict the course of cystic kidney disease.
Original languageEnglish
Awarding Institution
  • Erasmus University Rotterdam
Supervisors/Advisors
  • Hoorn, Ewout, Supervisor
  • Zietse, R., Supervisor
  • Salih, Mahdi, Co-supervisor
Award date11 May 2022
Place of PublicationRotterdam
Print ISBNs9789463616850
Publication statusPublished - 11 May 2022

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