TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2

S Venkatesan, M Hoogstraat, E Caljouw, T Pierson, Jochem Spoor, Lona Moradi - Zeneyedpour, Erik jan Dubbink, Lennard Dekker, Mariëlle van der Kaaij, Jenneke Kloezeman, Lotte Berghauser Pont, N J M Besselink, Theo Luider, J Joore, John Martens, Martine Lamfers, Stefan Sleijfer, Sieger Leenstra

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)
11 Downloads (Pure)
Original languageUndefined/Unknown
Pages (from-to)58435-58444
Number of pages10
Issue number36
Publication statusPublished - 2016

Research programs

  • EMC MM-03-24-01
  • EMC MM-03-44-06
  • EMC OR-01-45-01

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