Tracking in cell and developmental biology

Erik Meijering, Oleh Dzyubachyk, Ihor Smal, Gert van Cappellen

Research output: Contribution to journalArticleAcademicpeer-review

191 Citations (Scopus)

Abstract

The past decade has seen an unprecedented data explosion in biology. It has become evident that in order to take full advantage of the potential wealth of information hidden in the data produced by even a single experiment, visual inspection and manual analysis are no longer adequate. To ensure efficiency, consistency, and completeness in data processing and analysis, computational tools are essential. Of particular importance to many modern live-cell imaging experiments is the ability to automatically track and analyze the motion of objects in time-lapse microscopy images. This article surveys the recent literature in this area. Covering all scales of microscopic observation, from cells, down to molecules, and up to entire organisms, it discusses the latest trends and successes in the development and application of computerized tracking methods in cell and developmental biology. (C) 2009 Elsevier Ltd. All rights reserved.
Original languageUndefined/Unknown
Pages (from-to)894-902
Number of pages9
JournalSeminars in Cell & Developmental Biology
Volume20
Issue number8
DOIs
Publication statusPublished - 2009

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