TY - JOUR
T1 - Trajectories of recall memory as predictive of hearing impairment
T2 - A longitudinal cohort study
AU - Maharani, Asri
AU - Dawes, Piers
AU - Nazroo, James
AU - Tampubolon, Gindo
AU - Pendleton, Neil
AU - Bertelsen, Geir
AU - Cosh, Suzanne
AU - Cougnard-Grégoire, Audrey
AU - Delcourt, Cécile
AU - Constantinidou, Fofi
AU - Goedegebure, Andre
AU - Helmer, Catherine
AU - Arfan Ikram, M.
AU - Klaver, Caroline C.W.
AU - Klaver, Caroline C.W.
AU - Maharani, Asri
AU - Meester-Smoor, Magda
AU - Nael, Virginie
AU - Oosterloo, Neelke
AU - Pendleton, Neil
AU - Schirmer, Henrik
AU - Tampubolon, Gindo
AU - Tiemeier, Henning
AU - Tiemeier, Henning
N1 - Publisher Copyright:
Copyright: © 2020 Maharani et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2020/6
Y1 - 2020/6
N2 - Objectives Accumulating evidence points to a relationship between hearing function and cognitive ability in later life. However, the exact mechanisms of this relationship are still unclear. This study aimed to characterise latent cognitive trajectories in recall memory and identify their association with subsequent risk of hearing impairment. Methods We analysed data from the English Longitudinal Study of Ageing Wave 1 (2002/03) until Wave 7 (2014/15). The study population consisted of 3,615 adults aged 50+ who participated in the first wave of the English Longitudinal Study of Ageing, who had no self-reported hearing impairment in Wave 1, and who underwent a hearing test in Wave 7. Respondents were classified as having hearing impairment if they failed to hear tones quieter than 35 dB HL in the better ear. Results The trajectories of recall memory scores were grouped using latent class growth mixture modelling and were related to the presence of hearing impairment in Wave 7. Models estimating 1-class through 5-class recall memory trajectories were compared and the best-fitting models were 4-class trajectories. The different recall memory trajectories represent different starting points and mean of the memory scores. Compared to respondents with the highest recall memory trajectory, other trajectories were increasingly likely to develop later hearing impairment. Conclusions Long-term changes in cognitive ability predict hearing impairment. Further research is required to identify the mechanisms explaining the association between cognitive trajectories and hearing impairment, as well as to determine whether intervention for maintenance of cognitive function also give benefit on hearing function among older adults.
AB - Objectives Accumulating evidence points to a relationship between hearing function and cognitive ability in later life. However, the exact mechanisms of this relationship are still unclear. This study aimed to characterise latent cognitive trajectories in recall memory and identify their association with subsequent risk of hearing impairment. Methods We analysed data from the English Longitudinal Study of Ageing Wave 1 (2002/03) until Wave 7 (2014/15). The study population consisted of 3,615 adults aged 50+ who participated in the first wave of the English Longitudinal Study of Ageing, who had no self-reported hearing impairment in Wave 1, and who underwent a hearing test in Wave 7. Respondents were classified as having hearing impairment if they failed to hear tones quieter than 35 dB HL in the better ear. Results The trajectories of recall memory scores were grouped using latent class growth mixture modelling and were related to the presence of hearing impairment in Wave 7. Models estimating 1-class through 5-class recall memory trajectories were compared and the best-fitting models were 4-class trajectories. The different recall memory trajectories represent different starting points and mean of the memory scores. Compared to respondents with the highest recall memory trajectory, other trajectories were increasingly likely to develop later hearing impairment. Conclusions Long-term changes in cognitive ability predict hearing impairment. Further research is required to identify the mechanisms explaining the association between cognitive trajectories and hearing impairment, as well as to determine whether intervention for maintenance of cognitive function also give benefit on hearing function among older adults.
UR - http://www.scopus.com/inward/record.url?scp=85086692782&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0234623
DO - 10.1371/journal.pone.0234623
M3 - Article
C2 - 32555743
AN - SCOPUS:85086692782
SN - 1932-6203
VL - 15
JO - PLoS ONE
JF - PLoS ONE
IS - 6
M1 - e0234623
ER -