Translational Optical Imaging in Diagnosis and Treatment of Cancer

Stijn Keereweer, M Hutteman, JDF Kerrebijn, CJH van de Velde, AL Vahrmeijer, Clemens Löwik

Research output: Contribution to journalArticleAcademic

18 Citations (Scopus)


In cancer imaging, many different modalities are used that each have their specific features, leading to the combined use of different techniques for the detection, staging and treatment evaluation of cancer. Optical imaging using near-infrared fluorescence light is a new imaging modality that has recently emerged in the field of cancer imaging. After extensive preclinical research, the first steps of translation to the clinical practice are currently being made. In this article, we discuss the preclinical and clinical results of near-infrared optical imaging for non-invasive detection and classification of tumors, therapy monitoring, sentinel lymph node procedures, and image-guided cancer surgery. Widespread availability of imaging systems and optical contrast agents will enable larger studies on their clinical benefit and can help establish a definitive role in clinical practice.
Original languageUndefined/Unknown
Pages (from-to)498-503
Number of pages6
JournalCurrent Pharmaceutical Biotechnology
Issue number4
Publication statusPublished - 2012

Research programs

  • EMC OR-01-62-02

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