Transplant in older adults with AML: genomic wheat and chaff

Sylvie D. Freeman, Peter Valk

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

1 Citation (Scopus)


In this issue of Blood, Murdock et al(1) apply extensive diagnostic molecular profiling and measurable residual disease (MRD) detection of persistent mutations in a real-world cohort of older adults with acute myeloid leukemia (AML) to extract the most useful predictors of relapse-free survival (RFS) after allogeneic transplantation in first remission. Their results indicate that molecular persistence in remission is frequent in older adults and does not retain prognostic value for posttransplant outcomes after adjusting for specific baseline molecular and clinical variables.
Original languageEnglish
Pages (from-to)3459-3461
Number of pages3
Issue number24
Publication statusPublished - 16 Jun 2022

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