Tranylcypromine in narcolepsy

H. B.P.E. Gernaat; P. M.J. Haffmans; H. Knegtering; T. K. Birkenhager

doi:10.1055/s-2007-979599

Tranylcypromine in narcolepsy

H. B.P.E. Gernaat
, P. M.J. Haffmans
, H. Knegtering
, T. K. Birkenhager^*

^*Corresponding author for this work

Bloemendaal Psychiatric Centre

Research output: Contribution to journal › Article › Academic › peer-review

9 Citations (Scopus)

Abstract

The narcolepsy syndrome consists of excessive daytime somnolence, cataplexy, hallucinations, and sleep paralysis. Data on the effects of tranylcypromine are scant. We report on a patient with severe narcolepsy in whom administration of tranylcypromine led to freedom from hallucinations, nightmares, sleep paralysis, and rapid eye movements (REM), with considerable amelioration of cataplexy and increased daytime alertness. Muscle atonia and low-voltage desynchronized cortical activity during REM sleep did not change. Tranylcypromine warrants further study in narcolepsy.

Original language	English
Pages (from-to)	98-100
Number of pages	3
Journal	Pharmacopsychiatry
Volume	28
Issue number	3
DOIs	https://doi.org/10.1055/s-2007-979599
Publication status	Published - 1995
Externally published	Yes

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SDG 3 Good Health and Well-being

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title = "Tranylcypromine in narcolepsy",

abstract = "The narcolepsy syndrome consists of excessive daytime somnolence, cataplexy, hallucinations, and sleep paralysis. Data on the effects of tranylcypromine are scant. We report on a patient with severe narcolepsy in whom administration of tranylcypromine led to freedom from hallucinations, nightmares, sleep paralysis, and rapid eye movements (REM), with considerable amelioration of cataplexy and increased daytime alertness. Muscle atonia and low-voltage desynchronized cortical activity during REM sleep did not change. Tranylcypromine warrants further study in narcolepsy.",

author = "Gernaat, \{H. B.P.E.\} and Haffmans, \{P. M.J.\} and H. Knegtering and Birkenhager, \{T. K.\}",

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language = "English",

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T1 - Tranylcypromine in narcolepsy

AU - Gernaat, H. B.P.E.

AU - Haffmans, P. M.J.

AU - Knegtering, H.

AU - Birkenhager, T. K.

PY - 1995

Y1 - 1995

N2 - The narcolepsy syndrome consists of excessive daytime somnolence, cataplexy, hallucinations, and sleep paralysis. Data on the effects of tranylcypromine are scant. We report on a patient with severe narcolepsy in whom administration of tranylcypromine led to freedom from hallucinations, nightmares, sleep paralysis, and rapid eye movements (REM), with considerable amelioration of cataplexy and increased daytime alertness. Muscle atonia and low-voltage desynchronized cortical activity during REM sleep did not change. Tranylcypromine warrants further study in narcolepsy.

AB - The narcolepsy syndrome consists of excessive daytime somnolence, cataplexy, hallucinations, and sleep paralysis. Data on the effects of tranylcypromine are scant. We report on a patient with severe narcolepsy in whom administration of tranylcypromine led to freedom from hallucinations, nightmares, sleep paralysis, and rapid eye movements (REM), with considerable amelioration of cataplexy and increased daytime alertness. Muscle atonia and low-voltage desynchronized cortical activity during REM sleep did not change. Tranylcypromine warrants further study in narcolepsy.

UR - https://www.scopus.com/pages/publications/0029008647

U2 - 10.1055/s-2007-979599

DO - 10.1055/s-2007-979599

M3 - Article

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AN - SCOPUS:0029008647

SN - 0176-3679

VL - 28

SP - 98

EP - 100

JO - Pharmacopsychiatry

JF - Pharmacopsychiatry

IS - 3

ER -

Tranylcypromine in narcolepsy

Abstract

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