Treatment of basal cell carcinomas in patients with nevoid basal cell carcinoma syndrome

Simone Geer-Rutten, JU Ostertag, GAM Krekels

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26 Citations (Scopus)


Nevoid basal cell carcinoma syndrome (NBCCS) is characterized by the development of multiple basal cell carcinomas (BCCs). A major problem for these patients is the enormous amount of BCCs which can invade in the deep underlying structures, especially in the face. Different treatment modalities are used in these patients; surgical excision, Mohs micrographic surgery, cryotherapy, photodynamic therapy, ablative laser therapy and topical 5% imiquimod. There is no evidence based advice how to treat a NBCCS patient. To give a review of the literature about the possible treatment modalities for the multiple BCCs in NBCCS patients. Literature consists mainly of case reports; no evidence based advice how to treat a NBCCS patient exists. Multiple treatments are available (surgical and non-surgical), and a lot of them can be combined. Treatment in a megasession is an option to diminish the medical and social inconvenience for the patient. None declared.
Original languageUndefined/Unknown
Pages (from-to)308-313
Number of pages6
JournalJournal of the European Academy of Dermatology and Venereology
Issue number3
Publication statusPublished - 2009

Research programs

  • EMC MM-03-61-05-A

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