Treatment of hyperthyroid Graves' disease: a decisional approach

N. C. Schaper, M. G.M. Hunink, A. F. Casparie

Research output: Contribution to journalArticleAcademicpeer-review


Hyperthyroid Graves' disease can be treated with radioactive iodine, drugs or surgery. Literature shows no aggreement on these treatments, due in part to the different results of the various treatments that are reported. The authors tried to select a therapy by means of decision analysis, or to identify the most important variables affecting the decision. Probability estimates were derived from literature. No important differences between the three methods could be found. Analysis showed surgery to be preferable for younger patients and radioactive iodine for older patients, but sensitivity analysis showed that no specific therapy could be recommended. The age of the patient and the percentages of euthyreoidism acquired after therapy were the most important determinants.

Original languageEnglish
Pages (from-to)1443-1450
Number of pages8
JournalNederlands Tijdschrift voor Geneeskunde
Issue number32
Publication statusPublished - 9 Aug 1986


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