Treatment, outcome and predictionafter mild traumatic brain injury

Traumatic brain injury (TBI) is a sudden change in brain function or damage to the brain, caused by an external force. The majority of patients present with “mild” TBI. A substantial proportion of these patients suffer long term consequences in terms of physical disability, and incomplete return to the preinjury level of functioning. In this thesis, we aim to provide a better insight into the treatment and outcome of (mild) TBI and relations with sex/gender, age and comorbidity (PART 1), and to improve the identification of mild TBI patients with a higher risk of suboptimal short-term and longer-term outcomes (PART 2).