Abstract
This PhD research explores how infections with arboviruses transmitted by vectors, such as mosquitoes, can be serologically detected and diagnosed. With the ongoing rapid and worldwide spread of arboviruses, (closely-related) arboviruses increasingly co-circulate. This complicates serological interpretation and differentiation due to antibody cross-reactivity. This thesis aims to elucidate our understanding of the complex arbovirus antibody (background) patterns in low to high-risk populations, and ultimately to differentiate past and recent infections with closely-related viruses. The thesis describes various applications of innovative multiplex approaches to study arbovirus antibodies and their complex interplay.
| Original language | English |
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| Award date | 3 Dec 2025 |
| Place of Publication | Rotterdam |
| Print ISBNs | 978-94-6522-795-5 |
| Publication status | Published - 3 Dec 2025 |