Upregation of basic fibroblast growth factor during chronic rejection in intestinal transplants

E. A. Kouwenhoven; A. N. Stein-Oakley; P. Jablonski; J. N.M. Ijzermans; R. W.F. De Bruin; N. J. Thomson

doi:10.1097/00042737-199812000-00126

Upregation of basic fibroblast growth factor during chronic rejection in intestinal transplants

E. A. Kouwenhoven
, A. N. Stein-Oakley
, P. Jablonski
, J. N.M. Ijzermans
, R. W.F. De Bruin
, N. J. Thomson

Surgery

Alfred Health
Monash University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Long term survival of intestinal transplants is hampered by chronic rejection (CR). We have developed a rat model of CR after small bowel transplantation (SBT), demonstrating mesenteric infiltration and sclerosis, intimal proliferation of the vessels thickening of the muscularis and mucosal changes. the fibrogenic cytokine basic fibroblast growth factor (bFGF) could be involved in the tissue remodeling of CR.
Therefore, we investigated the bFGF gene and protein expression and distribution in chronically rejecting intestinal allografts.
[...]

Original language	English
Pages (from-to)	A35
Journal	European Journal of Gastroenterology and Hepatology
Volume	10
Issue number	12
DOIs	https://doi.org/10.1097/00042737-199812000-00126
Publication status	Published - Dec 1998

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title = "Upregation of basic fibroblast growth factor during chronic rejection in intestinal transplants",

abstract = "Long term survival of intestinal transplants is hampered by chronic rejection (CR). We have developed a rat model of CR after small bowel transplantation (SBT), demonstrating mesenteric infiltration and sclerosis, intimal proliferation of the vessels thickening of the muscularis and mucosal changes. the fibrogenic cytokine basic fibroblast growth factor (bFGF) could be involved in the tissue remodeling of CR. Therefore, we investigated the bFGF gene and protein expression and distribution in chronically rejecting intestinal allografts. [...]",

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AU - Kouwenhoven, E. A.

AU - Stein-Oakley, A. N.

AU - Jablonski, P.

AU - Ijzermans, J. N.M.

AU - De Bruin, R. W.F.

AU - Thomson, N. J.

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N2 - Long term survival of intestinal transplants is hampered by chronic rejection (CR). We have developed a rat model of CR after small bowel transplantation (SBT), demonstrating mesenteric infiltration and sclerosis, intimal proliferation of the vessels thickening of the muscularis and mucosal changes. the fibrogenic cytokine basic fibroblast growth factor (bFGF) could be involved in the tissue remodeling of CR. Therefore, we investigated the bFGF gene and protein expression and distribution in chronically rejecting intestinal allografts. [...]

AB - Long term survival of intestinal transplants is hampered by chronic rejection (CR). We have developed a rat model of CR after small bowel transplantation (SBT), demonstrating mesenteric infiltration and sclerosis, intimal proliferation of the vessels thickening of the muscularis and mucosal changes. the fibrogenic cytokine basic fibroblast growth factor (bFGF) could be involved in the tissue remodeling of CR. Therefore, we investigated the bFGF gene and protein expression and distribution in chronically rejecting intestinal allografts. [...]

UR - https://www.scopus.com/pages/publications/85026144792

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DO - 10.1097/00042737-199812000-00126

M3 - Article

AN - SCOPUS:85026144792

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JO - European Journal of Gastroenterology and Hepatology

JF - European Journal of Gastroenterology and Hepatology

IS - 12

ER -

Upregation of basic fibroblast growth factor during chronic rejection in intestinal transplants

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