Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

ENSAT EURINE-ACT Investigators; Irina Bancos; Angela E. Taylor; Vasileios Chortis; Alice J. Sitch; Carl Jenkinson; Caroline J. Davidge-Pitts; Katharina Lang; Stylianos Tsagarakis; Magdalena Macech; Anna Riester; Timo Deutschbein; Ivana D. Pupovac; Tina Kienitz; Alessandro Prete; Thomas Papathomas; Lorna C. Gilligan; Cristian Bancos; Giuseppe Reimondo; Magalie Haissaguerre; Ljiljana Marina; Marianne A. Grytaas; Ahmed Sajwani; Katharina Langton; Hannah E. Ivison; Cedric H.L. Shackleton; Dana Erickson; Miriam Asia; Sotiria Palimeri; Agnieszka Kondracka; Adriani Spyroglou; Cristina L. Ronchi; Richard A. Feelders; Jonathan J. Deeks; Wiebke Arlt

doi:10.1016/s2213-8587(20)30218-7

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

ENSAT EURINE-ACT Investigators, Irina Bancos, Angela E. Taylor, Vasileios Chortis, Alice J. Sitch, Carl Jenkinson, Caroline J. Davidge-Pitts, Katharina Lang, Stylianos Tsagarakis, Magdalena Macech, Anna Riester, Timo Deutschbein, Ivana D. Pupovac, Tina Kienitz, Alessandro Prete, Thomas Papathomas, Lorna C. Gilligan, Cristian Bancos, Giuseppe Reimondo, Magalie HaissaguerreLjiljana Marina, Marianne A. Grytaas, Ahmed Sajwani, Katharina Langton, Hannah E. Ivison, Cedric H.L. Shackleton, Dana Erickson, Miriam Asia, Sotiria Palimeri, Agnieszka Kondracka, Adriani Spyroglou, Cristina L. Ronchi, Richard A. Feelders, Jonathan J. Deeks, Wiebke Arlt^*

^*Corresponding author for this work

Internal Medicine

Research output: Contribution to journal › Article › Academic › peer-review

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Original language	English
Pages (from-to)	773-781
Number of pages	9
Journal	The Lancet Diabetes & Endocrinology
Volume	8
Issue number	9
Early online date	23 Jul 2020
DOIs	https://doi.org/10.1016/s2213-8587(20)30218-7
Publication status	Published - Sept 2020

Bibliographical note

This work was supported by the European Commission under the Seventh Framework Programme (FP7/2007–13, grant agreement 259735, ENSATCANCER, awarded to GE, MF, FB, and WA), the UK Medical Research Council UK (Strategic Biomarker Grant G0801473 awarded to WA), the Claire Khan Trust Fund at University Hospitals Birmingham Charities (project grant to WA), the Mayo Clinic Foundation for Medical Education and Research (Mayo Scholarship awarded to IB), and the Wellcome Trust (Clinical Research Training Fellowship WT101671 awarded to VC). This research was also partly supported by the National Institute of Diabetes and Digestive and Kidney Diseases of the US National Institutes of Health (NIH), under award K23DK121888 (IB). JJD is a National Institute for Health Research (NIHR) Senior Investigator and AJS, JJD, and WA receive support from the NIHR Birmingham Biomedical Research Centre at the University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham (BRC-1215-20009)

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Cite this

ENSAT EURINE-ACT Investigators, Bancos, I., Taylor, A. E., Chortis, V., Sitch, A. J., Jenkinson, C., Davidge-Pitts, C. J., Lang, K., Tsagarakis, S., Macech, M., Riester, A., Deutschbein, T., Pupovac, I. D., Kienitz, T., Prete, A., Papathomas, T., Gilligan, L. C., Bancos, C., Reimondo, G., ... Arlt, W. (2020). Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study. The Lancet Diabetes & Endocrinology, 8(9), 773-781. https://doi.org/10.1016/s2213-8587(20)30218-7

@article{bcfb822d66a44e4bb54036b96fdc637f,

title = "Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study",

author = "{ENSAT EURINE-ACT Investigators} and Irina Bancos and Taylor, {Angela E.} and Vasileios Chortis and Sitch, {Alice J.} and Carl Jenkinson and Davidge-Pitts, {Caroline J.} and Katharina Lang and Stylianos Tsagarakis and Magdalena Macech and Anna Riester and Timo Deutschbein and Pupovac, {Ivana D.} and Tina Kienitz and Alessandro Prete and Thomas Papathomas and Gilligan, {Lorna C.} and Cristian Bancos and Giuseppe Reimondo and Magalie Haissaguerre and Ljiljana Marina and Grytaas, {Marianne A.} and Ahmed Sajwani and Katharina Langton and Ivison, {Hannah E.} and Shackleton, {Cedric H.L.} and Dana Erickson and Miriam Asia and Sotiria Palimeri and Agnieszka Kondracka and Adriani Spyroglou and Ronchi, {Cristina L.} and Feelders, {Richard A.} and Deeks, {Jonathan J.} and Wiebke Arlt and Leo Hofland and Hans Hofland",

note = "This work was supported by the European Commission under the Seventh Framework Programme (FP7/2007–13, grant agreement 259735, ENSATCANCER, awarded to GE, MF, FB, and WA), the UK Medical Research Council UK (Strategic Biomarker Grant G0801473 awarded to WA), the Claire Khan Trust Fund at University Hospitals Birmingham Charities (project grant to WA), the Mayo Clinic Foundation for Medical Education and Research (Mayo Scholarship awarded to IB), and the Wellcome Trust (Clinical Research Training Fellowship WT101671 awarded to VC). This research was also partly supported by the National Institute of Diabetes and Digestive and Kidney Diseases of the US National Institutes of Health (NIH), under award K23DK121888 (IB). JJD is a National Institute for Health Research (NIHR) Senior Investigator and AJS, JJD, and WA receive support from the NIHR Birmingham Biomedical Research Centre at the University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham (BRC-1215-20009)",

year = "2020",

month = sep,

doi = "10.1016/s2213-8587(20)30218-7",

language = "English",

volume = "8",

pages = "773--781",

journal = "The Lancet Diabetes & Endocrinology",

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number = "9",

}

ENSAT EURINE-ACT Investigators, Bancos, I, Taylor, AE, Chortis, V, Sitch, AJ, Jenkinson, C, Davidge-Pitts, CJ, Lang, K, Tsagarakis, S, Macech, M, Riester, A, Deutschbein, T, Pupovac, ID, Kienitz, T, Prete, A, Papathomas, T, Gilligan, LC, Bancos, C, Reimondo, G, Haissaguerre, M, Marina, L, Grytaas, MA, Sajwani, A, Langton, K, Ivison, HE, Shackleton, CHL, Erickson, D, Asia, M, Palimeri, S, Kondracka, A, Spyroglou, A, Ronchi, CL, Feelders, RA, Deeks, JJ & Arlt, W 2020, 'Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study', The Lancet Diabetes & Endocrinology, vol. 8, no. 9, pp. 773-781. https://doi.org/10.1016/s2213-8587(20)30218-7

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study. / ENSAT EURINE-ACT Investigators; Bancos, Irina; Taylor, Angela E. et al.
In: The Lancet Diabetes & Endocrinology, Vol. 8, No. 9, 09.2020, p. 773-781.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study

T2 - a prospective test validation study

AU - ENSAT EURINE-ACT Investigators

AU - Bancos, Irina

AU - Taylor, Angela E.

AU - Chortis, Vasileios

AU - Sitch, Alice J.

AU - Jenkinson, Carl

AU - Davidge-Pitts, Caroline J.

AU - Lang, Katharina

AU - Tsagarakis, Stylianos

AU - Macech, Magdalena

AU - Riester, Anna

AU - Deutschbein, Timo

AU - Pupovac, Ivana D.

AU - Kienitz, Tina

AU - Prete, Alessandro

AU - Papathomas, Thomas

AU - Gilligan, Lorna C.

AU - Bancos, Cristian

AU - Reimondo, Giuseppe

AU - Haissaguerre, Magalie

AU - Marina, Ljiljana

AU - Grytaas, Marianne A.

AU - Sajwani, Ahmed

AU - Langton, Katharina

AU - Ivison, Hannah E.

AU - Shackleton, Cedric H.L.

AU - Erickson, Dana

AU - Asia, Miriam

AU - Palimeri, Sotiria

AU - Kondracka, Agnieszka

AU - Spyroglou, Adriani

AU - Ronchi, Cristina L.

AU - Feelders, Richard A.

AU - Deeks, Jonathan J.

AU - Arlt, Wiebke

AU - Hofland, Leo

AU - Hofland, Hans

N1 - This work was supported by the European Commission under the Seventh Framework Programme (FP7/2007–13, grant agreement 259735, ENSATCANCER, awarded to GE, MF, FB, and WA), the UK Medical Research Council UK (Strategic Biomarker Grant G0801473 awarded to WA), the Claire Khan Trust Fund at University Hospitals Birmingham Charities (project grant to WA), the Mayo Clinic Foundation for Medical Education and Research (Mayo Scholarship awarded to IB), and the Wellcome Trust (Clinical Research Training Fellowship WT101671 awarded to VC). This research was also partly supported by the National Institute of Diabetes and Digestive and Kidney Diseases of the US National Institutes of Health (NIH), under award K23DK121888 (IB). JJD is a National Institute for Health Research (NIHR) Senior Investigator and AJS, JJD, and WA receive support from the NIHR Birmingham Biomedical Research Centre at the University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham (BRC-1215-20009)

PY - 2020/9

Y1 - 2020/9

U2 - 10.1016/s2213-8587(20)30218-7

DO - 10.1016/s2213-8587(20)30218-7

M3 - Article

C2 - 32711725

SN - 2213-8587

VL - 8

SP - 773

EP - 781

JO - The Lancet Diabetes & Endocrinology

JF - The Lancet Diabetes & Endocrinology

IS - 9

ER -