Vaccine design and delivery approaches for COVID-19

Kiana Shahzamani; Fatemeh Mahmoudian; Shahrzad Ahangarzadeh; Mohammad Mehdi Ranjbar; Leila Beikmohammadi; Samira Bahrami; Elmira Mohammadi; Sahar Esfandyari; Abbas Alibakhshi; Shaghayegh Haghjooy Javanmard

doi:10.1016/j.intimp.2021.108086

Vaccine design and delivery approaches for COVID-19

Kiana Shahzamani, Fatemeh Mahmoudian, Shahrzad Ahangarzadeh, Mohammad Mehdi Ranjbar, Leila Beikmohammadi, Samira Bahrami, Elmira Mohammadi, Sahar Esfandyari, Abbas Alibakhshi^*, Shaghayegh Haghjooy Javanmard^*

^*Corresponding author for this work

Biochemistry

Research output: Contribution to journal › Review article › Academic › peer-review

23 Citations (Scopus)

Abstract

COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.

Original language	English
Article number	108086
Journal	International Immunopharmacology
Volume	100
Early online date	23 Aug 2021
DOIs	https://doi.org/10.1016/j.intimp.2021.108086
Publication status	Published - Nov 2021

Bibliographical note

Funding Information:
The project was supported by Isfahan University of Medical Sciences [grant number: 198231]. The authors would like to thank infectious Diseases and Tropical Medicine Research Center for kind supports.

Publisher Copyright:
© 2021 Elsevier B.V.

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.intimp.2021.108086

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380485/

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title = "Vaccine design and delivery approaches for COVID-19",

abstract = "COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.",

author = "Kiana Shahzamani and Fatemeh Mahmoudian and Shahrzad Ahangarzadeh and Ranjbar, {Mohammad Mehdi} and Leila Beikmohammadi and Samira Bahrami and Elmira Mohammadi and Sahar Esfandyari and Abbas Alibakhshi and Javanmard, {Shaghayegh Haghjooy}",

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AU - Mahmoudian, Fatemeh

AU - Ahangarzadeh, Shahrzad

AU - Ranjbar, Mohammad Mehdi

AU - Beikmohammadi, Leila

AU - Bahrami, Samira

AU - Mohammadi, Elmira

AU - Esfandyari, Sahar

AU - Alibakhshi, Abbas

AU - Javanmard, Shaghayegh Haghjooy

N1 - Funding Information: The project was supported by Isfahan University of Medical Sciences [grant number: 198231]. The authors would like to thank infectious Diseases and Tropical Medicine Research Center for kind supports. Publisher Copyright: © 2021 Elsevier B.V.

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AB - COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.

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Vaccine design and delivery approaches for COVID-19

Abstract

Bibliographical note

UN SDGs

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