Vaccine hesitancy comes in waves: Longitudinal evidence on willingness to vaccinate against COVID-19 from seven European countries

Iryna Sabat*, Sebastian Neumann-Böhme, Pedro Pita Barros, Aleksandra Torbica, Job van Exel, Werner Brouwer, Tom Stargardt, Jonas Schreyögg

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Aim:
This paper investigates the prevalence and determinants of three main states of people's willingness to be vaccinated (WTBV) against COVID-19 – willing, unwilling and hesitant – and the occurrence and predictors of shifts between these states over time. Understanding the dynamics of vaccine intentions is crucial for developing targeted campaigns to increase uptake and emergency response preparedness.

Study design:
A panel survey consisting of 9 quarterly waves of data collected between April 2020 and January 2022. Baseline data included 24 952 adults from Germany, UK, Denmark, the Netherlands, France, Portugal, and Italy recruited from online panels to construct census-matched nationally representative samples.

Methods and measures:
Self-reported COVID-19 vaccine intention was the main outcome. Multinomial logit random effects models were used to analyze the relationships of interest. All results reported as relative risk ratios (RRR).

Results:
Hesitancy to get vaccinated was the most unstable vaccine intention, with on average 42% of ever hesitant respondents remaining in this state through future waves, followed by the ‘unwilling’ (53%) and ‘willing (82%). Following COVID-19 news, trust in information from the government, GPs and the WHO, risk preferences, risk perceptions, and confidence in vaccines (or lack thereof) predicted vaccination intention reversals. Risk preferences acted both as an impediment and as a facilitator for the vaccine uptake depending on the initial vaccine intention.

Conclusions and relevance:
This study revealed the dynamic nature of COVID-19 vaccine intentions and its predictors in 7 European countries. The findings provide insights to policymakers for designing more effective communication strategies, particularly targeted at hesitant and unwilling to vaccinate population groups, to increase vaccine uptake for future public health emergencies.

Original languageEnglish
Pages (from-to)5304-5312
Number of pages9
JournalVaccine
Volume41
Issue number36
DOIs
Publication statusPublished - 14 Aug 2023

Bibliographical note

Funding Information:
Authors’ contributions: All authors contributed to the manuscript. IS, TS and JS conceptualized the idea and developed the methodology of the study. IS conducted the formal analysis, investigation and data visualizations and wrote the original draft. JE, JS, TS, PPB, WB, SNB and AT provided critical revisions and validation. IS and SNB equally contributed to the design and implementation of the survey with expertise and feedback from PPB, WB, JE, AT, JS and TS. Tom Stargardt and Jonas Schreyögg equally contributed to the study and should be regarded as Senior authors. Iryna Sabat, Jonas Schreyögg, Tom Stargardt, had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Funding: This project received funding from the Horizon 2020 Research and Innovation Programme of the European Union through the Marie Skłodowska-Curie Grant Agreement No. 721402 coordinated by the University of Hamburg in Germany and was further funded by the German Research Foundation (DFG) under grant number 466310982. The work was also supported by funding under the Excellence Strategy by the German federal and state governments, as well as by the University of Hamburg, Erasmus University Rotterdam, Bocconi University and Nova School of Business& Economics Lisbon – Chair BPI | “Fundacão La Caixa” on Health Economics. Role of the Funder/Sponsor: The Funding organisations had no role in the design and conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication. Conflict of Interest Disclosures: All authors have completed the ICMJE Form for Disclosure of Potential Conflicts of Interest (available on request from the corresponding author) and declare: no financial relationships with any organizations that might have an interest in the submitted work, no other relationships or activities that could appear to have influenced the submitted work. Disclaimer: Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the affiliated institutions. Additional Contributions: We would like to thank our colleagues in the ECOS consortium for their cooperation in this project. We especially want to thank our translators Joana Pestana, Elisabetta Oliveri, Maarten Husen, Julien Bergeot, Lasse Falk, who translated the questionnaire into their native languages.

Publisher Copyright:
© 2023 The Authors

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