Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

A Deichmann; S Hacein-Bey-Abina; M Schmidt; A Garrigue; MH (Martijn) Brugman; J Hu; H Glimm; G Gyapay; B Prum; CC Fraser; N Fischer; K Schwarzwaelder; ML Siegler; D (Dirk) de Ridder; Karin Overzet; SJ Howe; AJ Thrasher; Gerard Wagemaker; U Abel; Frank Staal; E Delabesse; JL Villeval; B Aronow; C Hue; C Prinz; M Wissler; C Klanke; J Weissenbach; I Alexander; A Fischer; C von Kalle; M Cavazzana-Calvo

doi:10.1172/JCI31659

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

A Deichmann, S Hacein-Bey-Abina, M Schmidt, A Garrigue, MH (Martijn) Brugman, J Hu, H Glimm, G Gyapay, B Prum, CC Fraser, N Fischer, K Schwarzwaelder, ML Siegler, D (Dirk) de Ridder, Karin Overzet, SJ Howe, AJ Thrasher, Gerard Wagemaker, U Abel, Frank StaalE Delabesse, JL Villeval, B Aronow, C Hue, C Prinz, M Wissler, C Klanke, J Weissenbach, I Alexander, A Fischer, C von Kalle, M Cavazzana-Calvo

Research output: Contribution to journal › Article › Academic › peer-review

227 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	2225-2232
Number of pages	8
Journal	Journal of Clinical Investigation
Volume	117
Issue number	8
DOIs	https://doi.org/10.1172/JCI31659
Publication status	Published - 2007

Research programs

EMC MM-02-41-04
EMC MM-02-72-01

Access to Document

10.1172/JCI31659

http://hdl.handle.net/1765/35291

Cite this

Deichmann, A., Hacein-Bey-Abina, S., Schmidt, M., Garrigue, A., Brugman, MH., Hu, J., Glimm, H., Gyapay, G., Prum, B., Fraser, CC., Fischer, N., Schwarzwaelder, K., Siegler, ML., de Ridder, D., Overzet, K., Howe, SJ., Thrasher, AJ., Wagemaker, G., Abel, U., ... Cavazzana-Calvo, M. (2007). Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy. Journal of Clinical Investigation, 117(8), 2225-2232. https://doi.org/10.1172/JCI31659

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Deichmann, A, Hacein-Bey-Abina, S, Schmidt, M, Garrigue, A, Brugman, MH, Hu, J, Glimm, H, Gyapay, G, Prum, B, Fraser, CC, Fischer, N, Schwarzwaelder, K, Siegler, ML, de Ridder, D, Overzet, K, Howe, SJ, Thrasher, AJ, Wagemaker, G, Abel, U, Staal, F, Delabesse, E, Villeval, JL, Aronow, B, Hue, C, Prinz, C, Wissler, M, Klanke, C, Weissenbach, J, Alexander, I, Fischer, A, von Kalle, C & Cavazzana-Calvo, M 2007, 'Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy', Journal of Clinical Investigation, vol. 117, no. 8, pp. 2225-2232. https://doi.org/10.1172/JCI31659

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T1 - Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

AU - Deichmann, A

AU - Hacein-Bey-Abina, S

AU - Schmidt, M

AU - Garrigue, A

AU - Brugman, MH (Martijn)

AU - Hu, J

AU - Glimm, H

AU - Gyapay, G

AU - Prum, B

AU - Fraser, CC

AU - Fischer, N

AU - Schwarzwaelder, K

AU - Siegler, ML

AU - de Ridder, D (Dirk)

AU - Overzet, Karin

AU - Howe, SJ

AU - Thrasher, AJ

AU - Wagemaker, Gerard

AU - Abel, U

AU - Staal, Frank

AU - Delabesse, E

AU - Villeval, JL

AU - Aronow, B

AU - Hue, C

AU - Prinz, C

AU - Wissler, M

AU - Klanke, C

AU - Weissenbach, J

AU - Alexander, I

AU - Fischer, A

AU - von Kalle, C

AU - Cavazzana-Calvo, M

PY - 2007

Y1 - 2007

U2 - 10.1172/JCI31659

DO - 10.1172/JCI31659

M3 - Article

C2 - 17671652

SN - 0021-9738

VL - 117

SP - 2225

EP - 2232

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

IS - 8

ER -