Wavelength multiplexing for FD-OCT speckle averaging

Gijs Van Soest; Evelyn Regar; Brett E. Bouma; Guillermo J. Tearney; Antonius F.W. Van Der Steen

doi:10.1117/12.906335

Wavelength multiplexing for FD-OCT speckle averaging

Gijs Van Soest^*
, Evelyn Regar
, Brett E. Bouma
, Guillermo J. Tearney
, Antonius F.W. Van Der Steen

^*Corresponding author for this work

Cardiology

Massachusetts General Hospital
Erasmus University Rotterdam
Royal Netherlands Academy of Arts and Sciences

Research output: Chapter/Conference proceeding › Conference proceeding › Academic › peer-review

Abstract

Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging. We demonstrate this technique using in vivo intravascular optical frequency domain imaging (OFDI) data.

Original language	English
Title of host publication	Photonic Therapeutics and Diagnostics VIII
DOIs	https://doi.org/10.1117/12.906335
Publication status	Published - 9 Feb 2012
Event	Photonic Therapeutics and Diagnostics VIII - San Francisco, CA, United States Duration: 21 Jan 2012 → 24 Jan 2012

Publication series

Series	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8207
ISSN	1605-7422

Conference

Conference	Photonic Therapeutics and Diagnostics VIII
Country/Territory	United States
City	San Francisco, CA
Period	21/01/12 → 24/01/12

Bibliographical note

Funding Information:
This work was supported by grants from the National Institutes of Health: GM23509 (K.J.B.), GM34469 (K.J.B.), CA47795 (K.J.B.), RR04328 (E.F.), NS24520 (E.F.), and GM37911 (E.F.).

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title = "Wavelength multiplexing for FD-OCT speckle averaging",

abstract = "Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging. We demonstrate this technique using in vivo intravascular optical frequency domain imaging (OFDI) data.",

author = "\{Van Soest\}, Gijs and Evelyn Regar and Bouma, \{Brett E.\} and Tearney, \{Guillermo J.\} and \{Van Der Steen\}, \{Antonius F.W.\}",

note = "Funding Information: This work was supported by grants from the National Institutes of Health: GM23509 (K.J.B.), GM34469 (K.J.B.), CA47795 (K.J.B.), RR04328 (E.F.), NS24520 (E.F.), and GM37911 (E.F.).; Photonic Therapeutics and Diagnostics VIII ; Conference date: 21-01-2012 Through 24-01-2012",

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Van Soest, G, Regar, E, Bouma, BE, Tearney, GJ & Van Der Steen, AFW 2012, Wavelength multiplexing for FD-OCT speckle averaging. in Photonic Therapeutics and Diagnostics VIII., 820742, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8207, Photonic Therapeutics and Diagnostics VIII, San Francisco, CA, United States, 21/01/12. https://doi.org/10.1117/12.906335

TY - GEN

T1 - Wavelength multiplexing for FD-OCT speckle averaging

AU - Van Soest, Gijs

AU - Regar, Evelyn

AU - Bouma, Brett E.

AU - Tearney, Guillermo J.

AU - Van Der Steen, Antonius F.W.

N1 - Funding Information: This work was supported by grants from the National Institutes of Health: GM23509 (K.J.B.), GM34469 (K.J.B.), CA47795 (K.J.B.), RR04328 (E.F.), NS24520 (E.F.), and GM37911 (E.F.).

PY - 2012/2/9

Y1 - 2012/2/9

N2 - Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging. We demonstrate this technique using in vivo intravascular optical frequency domain imaging (OFDI) data.

AB - Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging. We demonstrate this technique using in vivo intravascular optical frequency domain imaging (OFDI) data.

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U2 - 10.1117/12.906335

DO - 10.1117/12.906335

M3 - Conference proceeding

AN - SCOPUS:84860717524

SN - 9780819488503

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Photonic Therapeutics and Diagnostics VIII

T2 - Photonic Therapeutics and Diagnostics VIII

Y2 - 21 January 2012 through 24 January 2012

ER -

Wavelength multiplexing for FD-OCT speckle averaging

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