Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future

AS Darwich; K Ogungbenro; AA Vinks; JR Powell; JL Reny; N Marsousi; Y Daali; D Fairman; J Cook; LJ Lesko; JS McCune; CAJ Knibbe; Saskia de Wildt; JS Leeder; M Neely; AF Zuppa; P Vicini; L Aarons; TN Johnson; J Boiani; A Rostami-Hodjegan

doi:10.1002/cpt.659

Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future

AS Darwich
, K Ogungbenro
, AA Vinks
, JR Powell
, JL Reny
, N Marsousi
, Y Daali
, D Fairman
, J Cook
, LJ Lesko
, JS McCune
, CAJ Knibbe
, Saskia de Wildt
, JS Leeder
, M Neely
, AF Zuppa
, P Vicini
, L Aarons
, TN Johnson
, J Boiani

A Rostami-Hodjegan

Neonatal and Pediatric Intensive Care

Research output: Contribution to journal › Article › Academic › peer-review

214 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	646-656
Number of pages	11
Journal	Clinical Pharmacology & Therapeutics
Volume	101
Issue number	5
DOIs	https://doi.org/10.1002/cpt.659
Publication status	Published - 2017

Research programs

EMC OR-01

Access to Document

10.1002/cpt.659

http://hdl.handle.net/1765/99424

Cite this

Darwich, AS., Ogungbenro, K., Vinks, AA., Powell, JR., Reny, JL., Marsousi, N., Daali, Y., Fairman, D., Cook, J., Lesko, LJ., McCune, JS., Knibbe, CAJ., de Wildt, S., Leeder, JS., Neely, M., Zuppa, AF., Vicini, P., Aarons, L., Johnson, TN., ... Rostami-Hodjegan, A. (2017). Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future. Clinical Pharmacology & Therapeutics, 101(5), 646-656. https://doi.org/10.1002/cpt.659

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Darwich, AS, Ogungbenro, K, Vinks, AA, Powell, JR, Reny, JL, Marsousi, N, Daali, Y, Fairman, D, Cook, J, Lesko, LJ, McCune, JS, Knibbe, CAJ, de Wildt, S, Leeder, JS, Neely, M, Zuppa, AF, Vicini, P, Aarons, L, Johnson, TN, Boiani, J & Rostami-Hodjegan, A 2017, 'Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future', Clinical Pharmacology & Therapeutics, vol. 101, no. 5, pp. 646-656. https://doi.org/10.1002/cpt.659

TY - JOUR

T1 - Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future

AU - Darwich, AS

AU - Ogungbenro, K

AU - Vinks, AA

AU - Powell, JR

AU - Reny, JL

AU - Marsousi, N

AU - Daali, Y

AU - Fairman, D

AU - Cook, J

AU - Lesko, LJ

AU - McCune, JS

AU - Knibbe, CAJ

AU - de Wildt, Saskia

AU - Leeder, JS

AU - Neely, M

AU - Zuppa, AF

AU - Vicini, P

AU - Aarons, L

AU - Johnson, TN

AU - Boiani, J

AU - Rostami-Hodjegan, A

PY - 2017

Y1 - 2017

U2 - 10.1002/cpt.659

DO - 10.1002/cpt.659

M3 - Article

C2 - 28182269

SN - 0009-9236

VL - 101

SP - 646

EP - 656

JO - Clinical Pharmacology & Therapeutics

JF - Clinical Pharmacology & Therapeutics

IS - 5

ER -